Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079882 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTHTTTHRB | |
| SCHEMBL31682011 | 0.79 | FABP4 (0.43) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL22080432 | 0.75 | TDP1 (0.61) | ALDH1A1LMNATHRBMEN1KMT2A | |
| SCHEMBL24257840 | 0.74 | POLB (0.51) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL24257838 | 0.74 | TDP1 (0.68) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL11887722 | 0.73 | ALDH1A1 (0.72) | ALDH1A1LMNAMAPTHTTTHRB | |
| SCHEMBL22080191 | 0.73 | HTT (0.58) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL16235161 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTHTTTHRB | |
| SCHEMBL23014628 | 0.72 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL5230414 | 0.71 | MAPT (0.76) | ALDH1A1LMNAMAPTHTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | ALDH1A1 1829/4885LMNA 3090/4885MAPT 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.