Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | IRS1 | P35568 | 2/20 | 0.47 |
| ▸ | GAB1 | Q13480 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079909 | 0.92 | AKT1 (0.48) | AKT1IRS1GAB1KDM4ETDP1 | |
| SCHEMBL22080431 | 0.91 | KDM4E (0.54) | MAPTSMN1; SMN2LMNAHTTAKT1 | |
| SCHEMBL31682088 | 0.85 | MCL1 (0.40) | TDP1PLA2G4BMCL1BCL2A1 | |
| SCHEMBL22080432 | 0.81 | TDP1 (0.61) | TP53SMN1; SMN2LMNATSHRTDP1 | |
| SCHEMBL22080190 | 0.81 | KDM4E (0.49) | SMN1; SMN2AKT1IRS1GAB1KDM4E | |
| SCHEMBL24257838 | 0.81 | TDP1 (0.68) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL24257905 | 0.81 | NPC1 (0.42) | TP53MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL3551452 | 0.80 | SMN1; SMN2 (0.63) | TP53MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL22079879 | 0.79 | KDM4E (0.57) | MAPTSMN1; SMN2AKT1IRS1GAB1 | |
| SCHEMBL3554413 | 0.79 | SMN1; SMN2 (0.65) | TP53MAPTSMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TP53 314/4885MAPT 3611/4885SMN1; SMN2 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.