Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 10/20 | 0.54 |
| ▸ | GAB1 | Q13480 | 3/20 | 0.54 |
| ▸ | IRS1 | P35568 | 2/20 | 0.54 |
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079909 | 0.93 | AKT1 (0.48) | KDM4EAKT1GAB1IRS1RARB | |
| SCHEMBL24257837 | 0.91 | TP53 (0.48) | KDM4EAKT1GAB1IRS1MAPT | |
| SCHEMBL22079879 | 0.87 | KDM4E (0.57) | KDM4EAKT1GAB1IRS1RARB | |
| SCHEMBL22080432 | 0.81 | TDP1 (0.61) | MEN1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL31682020 | 0.81 | TBXA2R (0.43) | KDM4EAKT1GAB1IRS1ALDH1A1 | |
| SCHEMBL31681966 | 0.81 | TBXA2R (0.43) | KDM4EAKT1GAB1IRS1ALDH1A1 | |
| SCHEMBL31682097 | 0.81 | TBXA2R (0.43) | KDM4EAKT1GAB1IRS1ALDH1A1 | |
| SCHEMBL22080190 | 0.80 | KDM4E (0.49) | KDM4EAKT1GAB1IRS1SMN1; SMN2 | |
| SCHEMBL24257838 | 0.78 | TDP1 (0.68) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22106155 | 0.78 | GHSR (0.38) | KDM4EAKT1GAB1IRS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | KDM4E 3938/4885AKT1 1118/4885GAB1 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.