Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24260410 | 0.84 | KDM1A (0.34) | KDM1AMAOAOPRK1CCR2 | |
| SCHEMBL14429810 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL24260614 | 0.73 | KDM1A (0.33) | KDM1AOPRK1 | |
| SCHEMBL7895027 | 0.71 | EPHX1 (0.36) | — | |
| SCHEMBL12226416 | 0.69 | PIK3CD (0.37) | KDM1AOPRK1 | |
| SCHEMBL24260478 | 0.66 | KDM1A (0.31) | KDM1AOPRK1 | |
| SCHEMBL1776380 | 0.66 | PIK3CD (0.40) | — | |
| SCHEMBL24260459 | 0.65 | METAP1 (0.30) | — | |
| SCHEMBL999449 | 0.64 | ALDH1A1 (0.61) | KDM1AMAOAMAOB | |
| SCHEMBL21974894 | 0.64 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPV2, TRPV3 | KDM1A 3270/4885MAOA 2372/4885OPRK1 25/4885 |
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPA1, TRPV2 | KDM1A 3019/4885MAOA 2726/4885OPRK1 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.