Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426813 | 1.00 | TSHR (0.37) | TSHRMAPK1PRKCARASGRP3TP53 | |
| SCHEMBL2426815 | 1.00 | TSHR (0.37) | TSHRMAPK1PRKCARASGRP3TP53 | |
| SCHEMBL9217328 | 0.81 | TSHR (0.37) | TSHRMAPK1TP53 | |
| SCHEMBL9217326 | 0.81 | TSHR (0.37) | TSHRMAPK1TP53 | |
| SCHEMBL9217333 | 0.81 | TSHR (0.37) | TSHRMAPK1TP53 | |
| SCHEMBL2426248 | 0.77 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL29402647 | 0.77 | TSHR (0.34) | TSHRMAPK1PRKCARASGRP3 | |
| SCHEMBL2426251 | 0.77 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL29403609 | 0.77 | TSHR (0.34) | TSHRMAPK1PRKCARASGRP3 | |
| SCHEMBL2426256 | 0.77 | TSHR (0.34) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970067-B1 | SELECTIVE HYDROGENATION OF ALDEHYDES WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH & CIE (CH) | 2017-08-16 | — | — | EP | disclosed |
| US-9714263-B2 | Selective hydrogenation of aldehydes with Ru/bidentate ligands complexes | FIRMENICH SA (CH) | 2017-07-25 | — | — | US | disclosed |
| US-20160039853-A1 | SELECTIVE HYDROGENATION OF ALDEHYDES WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2016-02-11 | — | — | US | disclosed |
| US-8222198-B2 | Perfuming nitriles | FIRMENICH SA (CH) | 2012-07-17 | — | — | US | disclosed |
| EP-2134318-B1 | PERFUMING NITRILES | FIRMENICH & CIE (CH) | 2011-09-07 | — | — | EP | disclosed |
| US-20100267607-A1 | PERFUMING NITRILES | FIRMENICH SA (CH) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039853-A1 | SELECTIVE HYDROGENATION OF ALDEHYDES WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | TSHR 2305/4885MAPK1 3267/4885PRKCA 4646/4885 |
| US-20100267607-A1 | PERFUMING NITRILES | TRPA1, NIT2, PNN | TSHR 4517/4885MAPK1 3432/4885PRKCA 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.