Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25828769 | 0.84 | KMT2A (0.50) | TLR2MDM4TP53KMT2A | |
| SCHEMBL29989314 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL3871700 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL29401179 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL30440863 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL13940186 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL118389 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL29824809 | 0.83 | MDM4 (0.52) | TLR2MDM4TP53CASP3CASP1 | |
| SCHEMBL6989365 | 0.83 | CASP1 (0.48) | SLC17A5MDM4TP53CASP3CASP1 | |
| SCHEMBL8139788 | 0.83 | CASP1 (0.48) | SLC17A5MDM4TP53CASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038417-A2 | MODIFIED IL-18 POLYPEPTIDES AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2022-02-24 | — | — | WO | disclosed |