SCHEMBL29401179

SCHEMBL29401179

C=CCOC(=O)NC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ CASP1 P29466 5/20 0.49
▸ CASP3 P42574 2/20 0.49
▸ KMT2A Q03164 1/20 0.48
▸ TLR2 O60603 2/20 0.47
▸ MDM2 Q00987 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118389 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL3871700 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL30440863 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL29989314 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL13940186 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL29824809 1.00 MDM4 (0.52) MDM4TP53CASP1CASP3KMT2A
SCHEMBL5967446 0.91 MDM4 (0.59) MDM4TP53CASP3KMT2ATLR2
SCHEMBL119637 0.91 MDM4 (0.59) MDM4TP53CASP3KMT2ATLR2
SCHEMBL29455664 0.91 MDM4 (0.59) MDM4TP53CASP3KMT2ATLR2
SCHEMBL119688 0.91 MDM4 (0.59) MDM4TP53CASP3KMT2ATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695268-A1 ANTIBACTERIAL COVALENT PEPTIDE INHIBITORS Université de Bordeaux (FR) 2026-02-18 — — EP disclosed
US-20260000784-A1 PEPTIDIC WATER-SOLUBLE DELIVERY SYSTEM OF ANTICANCER DRUGS HOSPITAL SANT JOAN DE DEU (ES) 2026-01-01 — — US disclosed
EP-4658667-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY Merck Sharp & Dohme LLC (US) 2025-12-10 — — EP disclosed
US-20250332300-A1 HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-10-30 — — US disclosed
EP-4565281-A1 SITE-SPECIFIC MODIFICATION BY A BBB-SHUTTLE OF ANTIBODY-BASED ENTITIES FOR CROSSING THE BLOOD-BRAIN BARRIER Gate2Brain, S.L. (ES) 2025-06-11 — — EP disclosed
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 — — CN disclosed
CN-115232196-B Polypeptide inhibitor for treating triple negative breast cancer and preparation method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2025-03-28 — — CN disclosed
CN-119552215-A Tumor targeting polypeptides, conjugates comprising same, compositions and uses 苏州星洲生物科技有限公司 2025-03-04 — — CN disclosed
EP-4499150-A1 PEPTIDIC WATER-SOLUBLE DELIVERY SYSTEM OF ANTICANCER DRUGS Hospital Sant Joan de Deu (ES) 2025-02-05 — — EP disclosed
WO-2024211999-A9 EXTRACELLULAR HSP90 (EHSP90)-TARGETED RADIOPHARMACEUTICALS AND USE THEREOF Fusion Pharmaceuticals Inc. (CA) 2025-01-16 — — WO disclosed
EP-4046996-A1 CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF Universität Bielefeld (DE) 2022-08-24 — — EP disclosed
WO-2022162332-A1 ANTIBIOTIC NATURAL PRODUCT ANALOGUES THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-08-04 — — WO disclosed
CN-109912686-B Stable polypeptide inhibitor targeting HDAC (Histone deacetylase) and application thereof 北京大学深圳研究生院 2022-07-05 — — CN disclosed
US-11353448-B2 Methods and compositions for quantifying metabolites and proteins from single cells CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-06-07 — — US disclosed
CN-111690041-B Polypeptide with anti-tumor activity and preparation method thereof 上海大学 2022-06-07 — — CN disclosed
CN-114437181-A GLP-1R/GCGR/GIPR triple receptor agonist and application thereof 深圳深创生物药业有限公司 2022-05-06 — — CN disclosed
WO-2022064052-A1 PEPTIDIC CONJUGATES OF SN38 USEFUL IN THE TREATMENT OF CANCER FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) 2022-03-31 — — WO disclosed
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 — — US disclosed
US-20220088146-A1 Melanocortin Receptor-Specific Peptide Formulations and Methods for Gastrointestinal Tract-Specific Delivery PALATIN TECHNOLOGIES INC (US) 2022-03-24 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R MDM4 4380/4885TP53 3497/4885CASP1 515/4885
US-20220088146-A1 Melanocortin Receptor-Specific Peptide Formulations and Methods for Gastrointestinal Tract-Specific Delivery MC3R, GIPR, MC1R MDM4 4773/4885TP53 3820/4885CASP1 4408/4885
US-20260000784-A1 PEPTIDIC WATER-SOLUBLE DELIVERY SYSTEM OF ANTICANCER DRUGS TP53, SGMS1, ABCB11 MDM4 1734/4885TP53 1/4885CASP1 690/4885
US-20250332300-A1 HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF ERBB2, EGFR, ERBB3 MDM4 2510/4885TP53 112/4885CASP1 3818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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