⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740666 | 0.89 | HTR6 (0.31) | — | |
| SCHEMBL24700173 | 0.82 | CYP2C9 (0.36) | — | |
| Hydrochloric Acid SCHEMBL23123290 | 0.81 | CYP2C9 (0.35) | — | |
| SCHEMBL12331148 | 0.72 | — | — | |
| SCHEMBL24717530 | 0.70 | LTA4H (0.33) | — | |
| SCHEMBL24718638 | 0.70 | LTA4H (0.33) | — | |
| SCHEMBL10191534 | 0.68 | LTA4H (0.34) | — | |
| SCHEMBL18627049 | 0.68 | — | — | |
| SCHEMBL12422034 | 0.67 | FYN (0.35) | — | |
| SCHEMBL12716816 | 0.67 | FYN (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040259-A1 | IMIDAZO[1,2-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-A]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-02-24 | — | — | WO | disclosed |