Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265205 | 0.89 | — | — | |
| SCHEMBL24718638 | 0.76 | LTA4H (0.33) | HTR6LTA4H | |
| SCHEMBL24717530 | 0.76 | LTA4H (0.33) | HTR6LTA4H | |
| SCHEMBL10191534 | 0.73 | LTA4H (0.34) | HTR6LTA4H | |
| SCHEMBL24700173 | 0.71 | CYP2C9 (0.36) | HTR6LTA4H | |
| SCHEMBL24740667 | 0.71 | KMT2A (0.31) | LTA4H | |
| Hydrochloric Acid SCHEMBL23123290 | 0.70 | CYP2C9 (0.35) | HTR6 | |
| SCHEMBL6863904 | 0.68 | — | — | |
| SCHEMBL12422034 | 0.67 | FYN (0.35) | HTR6LTA4H | |
| SCHEMBL12716816 | 0.67 | FYN (0.35) | HTR6LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261120-A1 | nSMASE2 INHIBITOR PRODRUGS WITH ENHANCED ORAL AND BRAIN EXPOSURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022261120-A1 | nSMASE2 INHIBITOR PRODRUGS WITH ENHANCED ORAL AND BRAIN EXPOSURES | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-12-15 | — | — | WO | disclosed |