Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 8/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267226 | 0.85 | TRPV4 (0.44) | TRPV4PGRAR | |
| SCHEMBL24031511 | 0.85 | PGR (0.47) | TRPV4PGRAR | |
| SCHEMBL24267357 | 0.74 | TRPV4 (0.38) | TRPV4PGRARNOS3NOS1 | |
| SCHEMBL31561766 | 0.74 | TRPV4 (0.43) | BCL2A1TRPV4PGRARIDO1 | |
| SCHEMBL5047623 | 0.72 | TRPV4 (0.52) | TRPV4ARNOS3NOS1ADRA1D | |
| SCHEMBL7787351 | 0.71 | TRPV4 (0.55) | TRPV4ARNOS3NOS1ADRA1D | |
| SCHEMBL8751343 | 0.71 | IDO1 (0.50) | KCNH2IDO1 | |
| Hydrochloric Acid SCHEMBL6486656 | 0.71 | TRPV4 (0.50) | TRPV4ARNOS3NOS1ADRA1D | |
| SCHEMBL15575031 | 0.71 | PGR (0.62) | BCL2A1TRPV4PGRAR | |
| SCHEMBL22565823 | 0.71 | PGR (0.62) | BCL2A1TRPV4PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |