Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236619 | 0.92 | P2RX7 (0.59) | P2RX7HSD11B1GRM5ALDH1A1RAB9A | |
| SCHEMBL29421283 | 0.85 | P2RX7 (0.51) | P2RX7GRM5RAB9AARCNR2 | |
| SCHEMBL19132713 | 0.82 | RORC (0.49) | P2RX7HSD11B1GRM5KDM4EGAA | |
| SCHEMBL19445811 | 0.80 | HSD11B1 (0.71) | HSD11B1GRM5ALDH1A1KDM4ERAB9A | |
| SCHEMBL28111220 | 0.80 | P2RX7 (0.49) | P2RX7GRM5ALDH1A1ARCNR2 | |
| SCHEMBL29421288 | 0.80 | P2RX7 (0.49) | P2RX7RAB9AARCNR2NPC1 | |
| SCHEMBL2590689 | 0.79 | GRM5 (0.80) | GRM5ALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL22449377 | 0.79 | GRM5 (0.80) | GRM5ALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL19132716 | 0.79 | RORC (0.47) | P2RX7HSD11B1GRM5KDM4EGAA | |
| SCHEMBL2246381 | 0.78 | GRM5 (0.82) | GRM5KDM4EGAACYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |