Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267354 | 0.80 | P2RX7 (0.54) | P2RX7CNR2ARGRM5KMT2A | |
| SCHEMBL28236619 | 0.77 | P2RX7 (0.59) | P2RX7AHRARGRM5KMT2A | |
| SCHEMBL27761583 | 0.75 | ALDH1A1 (0.55) | GRM5TSHRALDH1A1 | |
| SCHEMBL29590900 | 0.73 | GRM5 (0.68) | GRM5KMT2AALDH1A1 | |
| SCHEMBL7197995 | 0.73 | GRM5 (0.68) | GRM5KMT2AALDH1A1 | |
| SCHEMBL7218492 | 0.73 | GRM5 (0.68) | GRM5KMT2AALDH1A1 | |
| SCHEMBL23425256 | 0.73 | GRM5 (0.68) | GRM5KMT2AALDH1A1 | |
| SCHEMBL27630536 | 0.73 | P2RX7 (0.51) | P2RX7CNR2KMT2AMEN1TSHR | |
| SCHEMBL30592641 | 0.72 | P2RX7 (0.53) | P2RX7AHRCNR2ARGRM5 | |
| SCHEMBL29421279 | 0.72 | P2RX7 (0.46) | P2RX7AHRCNR2ARGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |