SCHEMBL2426965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2427316	0.92	TP53 (0.38)	TP53MDM2ALDH1A1MAPTKDM4E
	SCHEMBL2430337	0.90	PDE5A (0.40)	ALDH1A1KDM4EPDE5ASMN1; SMN2
	SCHEMBL2430527	0.85	PDE5A (0.40)	ALDH1A1MAPTKDM4EPDE5ALMNA
	SCHEMBL2428424	0.84	ALDH1A1 (0.46)	TP53MDM2ALDH1A1MAPTKDM4E
	SCHEMBL2432838	0.82	HTR7 (0.42)	ALDH1A1MAPTKDM4EPDE5AHTT
	SCHEMBL2430551	0.80	BRDT (0.39)	ALDH1A1KDM4EHPGD
	SCHEMBL2432159	0.80	NPC1 (0.37)	TP53ALDH1A1MAPTKDM4ELMNA
	SCHEMBL1136358	0.78	PDE5A (0.39)	ALDH1A1MAPTKDM4EPDE5AHTT
	SCHEMBL2522289	0.78	PDE5A (0.42)	TP53ALDH1A1MAPTKDM4EPDE5A
	SCHEMBL2427556	0.77	KMT2A (0.39)	MDM2ALDH1A1MAPTL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.