SCHEMBL2432838

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430337	0.92	PDE5A (0.40)	HTR7PDE5ANR3C1PGRNR3C2
	SCHEMBL1136358	0.91	PDE5A (0.39)	HTR7PDE5ANR3C1PGRNR3C2
	SCHEMBL2427316	0.89	TP53 (0.38)	PDE5AKDM4EALDH1A1SMN1; SMN2HTT
	SCHEMBL2430464	0.87	CNR2 (0.42)	PDE5ANR3C1PGRNR3C2AR
	SCHEMBL2434674	0.85	HDAC4 (0.40)	KDM4ESMN1; SMN2HSD17B10ALOX15HTT
	SCHEMBL2429913	0.85	NR3C1 (0.48)	HTR7PDE5ANR3C1PGRNR3C2
	SCHEMBL2429157	0.84	SIK1 (0.39)	KDM4EALDH1A1HSD17B10HTTCYP1A2
	SCHEMBL2433158	0.83	ALDH1A1 (0.39)	KDM4EALDH1A1KMT2ASMN1; SMN2HSD17B10
	SCHEMBL2426965	0.82	TP53 (0.37)	PDE5AKDM4EALDH1A1SMN1; SMN2HTT
	SCHEMBL2430527	0.81	PDE5A (0.40)	PDE5AKDM4EALDH1A1KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.