Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809964 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL2427291 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL668947 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL17424960 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| Hydrochloric Acid SCHEMBL6182013 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL20563025 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL17424932 | 0.81 | BAZ2B (0.49) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL668435 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL21262192 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL15465771 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729953-A2 | A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | claimed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | disclosed |
| EP-4274898-A2 | CHIMERIC RECEPTOR THERAPY | Precigen, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-4251278-A1 | HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES | Precigen, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022150732-A2 | CHIMERIC RECEPTOR THERAPY | PRECIGEN, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022115470-A1 | HUMAN PAPILLOMA VIRUS VACCINES AND USES OF THE SAME FOR HPV ASSOCIATED DISEASES | PRECIGEN, INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| US-20210300943-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | US | disclosed |
| EP-3625228-B1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-07 | — | — | EP | disclosed |
| EP-3820484-A1 | ROR-1 SPECIFIC CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF | Precigen, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-3810593-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2021-04-28 | — | — | EP | disclosed |
| EP-0496342-B1 | New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient | NIPPON KAYAKU KK (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0741709-A1 | AROMATIC 2-AMINO-IMIDAZOLE DERIVATIVES AS ALPHA-2A ADRENOCEPTOR AGONISTS | Allergan (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0729953-A2 | A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729934-A2 | A process for producing a 3-alkoxy-2-(substituted)benzoic acid or an ester thereof | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5530021-A | AGRICULTURAL INSECTICIDES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1996-06-25 | — | — | US | disclosed |
| WO-1995019968-A1 | AROMATIC 2-AMINO-IMIDAZOLE DERIVATIVES AS ALPHA-2A ADRENOCEPTOR AGONISTS | ALLERGAN (US) | 1995-07-27 | — | — | WO | disclosed |
| US-5378726-A | Insecticide, parasiticide | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0496342-A1 | New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300943-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | KDM4E 1495/4885ALDH1A1 3839/4885HSD17B10 2463/4885 |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | KDM4E 1571/4885ALDH1A1 468/4885HSD17B10 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.