Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668435 | 0.86 | KDM4E (0.43) | BAZ2BHPGDALDH1A1KDM4EHTT | |
| SCHEMBL2427488 | 0.81 | KDM4E (0.55) | HPGDALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL7809964 | 0.81 | KDM4E (0.53) | HPGDALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL667849 | 0.81 | ALDH1A1 (0.40) | BAZ2BHPGDALDH1A1KDM4EHTT | |
| SCHEMBL20563025 | 0.81 | KDM4E (0.50) | BAZ2BHPGDALDH1A1KDM4EPLK1 | |
| SCHEMBL19380554 | 0.80 | BAZ2B (0.46) | BAZ2BHPGDALDH1A1PLK1NPC1 | |
| SCHEMBL668947 | 0.80 | KDM4E (0.47) | HPGDALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL17424960 | 0.80 | KDM4E (0.47) | HPGDALDH1A1KDM4EHTTHSD17B10 | |
| SCHEMBL6002703 | 0.79 | MTNR1A (0.52) | BAZ2BKDM4EPLK1MTNR1A | |
| SCHEMBL7475478 | 0.77 | HPGD (0.39) | HPGDALDH1A1KDM4EHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |