SCHEMBL668435

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17424932	0.86	BAZ2B (0.49)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL668947	0.82	KDM4E (0.47)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL17424960	0.82	KDM4E (0.47)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL668910	0.82	MTNR1A (0.40)	ALDH1A1HPGDMTNR1ANPC1RAB9A
	SCHEMBL2427488	0.80	KDM4E (0.55)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL7809964	0.80	KDM4E (0.53)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL667849	0.80	ALDH1A1 (0.40)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL20563025	0.79	KDM4E (0.50)	KDM4EALDH1A1HPGDHTTHSD17B10
	SCHEMBL15844494	0.78	CTNNB1 (0.52)	KDM4EMTNR1A
	SCHEMBL669425	0.76	SMN1; SMN2 (0.38)	KDM4EALDH1A1HPGDHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.