SCHEMBL242786

SCHEMBL242786

Cc1cc(C)c(Oc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.43
ACHE P22303 1/20 0.39
AR P10275 1/20 0.39
CRHR1 P34998 3/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
MPI P34949 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
PTPN1 P18031 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798387 0.97 RAPGEF4 (0.41) RAPGEF4ACHEARCRHR1ALDH1A1
Phosphine SCHEMBL22634061 0.97 RAPGEF4 (0.41) RAPGEF4ACHEARCRHR1ALDH1A1
Methyl Alcohol SCHEMBL28790286 0.94 ALDH1A1 (0.39) RAPGEF4ACHEARCRHR1ALDH1A1
Methylamine SCHEMBL18641330 0.94 RAPGEF4 (0.39) RAPGEF4ACHEARCRHR1ALDH1A1
SCHEMBL11717917 0.89 RAPGEF4 (0.36) RAPGEF4ACHEARCRHR1ALDH1A1
SCHEMBL25968199 0.87 ALDH1A1 (0.52) RAPGEF4ARCRHR1ALDH1A1KDM4E
SCHEMBL11420240 0.80 RAPGEF4 (0.43) RAPGEF4ACHEALDH1A1KDM4EGAA
SCHEMBL26728849 0.79 PTPN1 (0.42) RAPGEF4ARCRHR1ALDH1A1MAPT
SCHEMBL11588965 0.79 TEAD4 (0.48) RAPGEF4ACHEARALDH1A1GAA
SCHEMBL129762 0.78 ACHE (0.57) RAPGEF4ACHEALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3504196-B1 PROCESSES FOR PREPARING OLAPARIB SCINOPHARM TAIWAN LTD (TW) 2026-04-08 EP claimed
EP-4217362-B1 REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST FIRMENICH & CIE (CH) 2026-03-18 EP claimed
EP-3980513-B1 DEWATERING OF THERMOCHEMICAL OIL PREEM AB (SE) 2025-12-24 EP claimed
EP-4107236-B1 IMPROVED SOLVENTS FOR ACETYLENE FLUID STORAGE PRAXAIR TECHNOLOGY INC (US) 2023-11-15 EP claimed
WO-2020018087-A1 POLYURETHANE FOAM ADDITIVES TO IMPROVE FOAM ADHESION TO ORGANIC POLYMERS EVONIK DEGUSSA GMBH (DE) 2020-01-23 WO claimed
EP-2010472-B1 METHOD FOR TREATING PHENOL INEOS PHENOL GMBH & CO KG (DE) 2013-07-24 EP claimed
US-7544845-B2 Process for treating phenol INEOS PHENOL GMBH & CO. KG (DE) 2009-06-09 US claimed
EP-2010472-A1 METHOD FOR TREATING PHENOL INEOS Phenol GmbH & Co. KG (DE) 2009-01-07 EP claimed
EP-2010471-A1 PROCESS FOR REMOVAL OF HYDROXYACETONE FORM PHENOL INEOS Phenol GmbH & Co. KG (DE) 2009-01-07 EP claimed
WO-2007118601-A1 PROCESS FOR REMOVAL OF HYDROXYACETONE FORM PHENOL INEOS PHENOL GMBH & CO. KG (DE) 2007-10-25 WO claimed
EP-0667848-B1 ISOPHORONE PROCESS ARISTECH CHEMICAL CORP (US) 1998-12-09 EP claimed
US-5578470-A USING CYSTEINE NEDERLANDSE ORGANISATIE VOOR TOEGEPAST (NL) 1996-11-26 US claimed
EP-0667848-A4 ISOPHORONE PROCESS. ARISTECH CHEMICAL CORP (US) 1996-01-10 EP claimed
EP-0667848-A1 ISOPHORONE PROCESS Aristech Chemical Corporation (US) 1995-08-23 EP claimed
US-5424470-A Unsaturated ketones as accelerators for hydrosilation DOW CORNING CORPORATION (US) 1995-06-13 US claimed
WO-1995007255-A1 ISOPHORONE PROCESS ARISTECH CHEMICAL CORPORATION (US) 1995-03-16 WO claimed
US-5352839-A Aldol condensation of acetone with removal of acetone, mesityl oxide and beta isophorone ARISTECH CHEMICAL CORPORATION (US) 1994-10-04 US claimed
US-4088703-A AS CYCLOHEXANOL; HYDROGENATION USING NICKEL CATALYST, DISTILLATION ALLIED CHEMICAL CORPORATION (US) 1978-05-09 US claimed
US-3974225-A Process for the preparation of unsaturated aldehydes FIRMENICH S.A. (CH) 1976-08-10 US claimed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US claimed