Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CBX7 | O95931 | 2/20 | 0.48 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415222 | 0.84 | RAD52 (1.00) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL25890248 | 0.77 | RAD52 (0.68) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL3201165 | 0.77 | ALDH1A1 (0.65) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL24195289 | 0.75 | RAD52 (0.67) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL29044109 | 0.74 | ALDH1A1 (0.50) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL28705162 | 0.74 | TP53 (0.55) | RAD52ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL28449922 | 0.73 | ALDH1A1 (0.81) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL29044123 | 0.72 | ALDH1A1 (0.51) | RAD52ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL38659116 | 0.71 | RAD52 (0.59) | RAD52ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL16377147 | 0.71 | RAD52 (0.63) | RAD52ALDH1A1TSHRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071484-A1 | 3-HYDROXYOXINDOLE DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2022-04-07 | — | — | WO | disclosed |