Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19080590 | 0.78 | TDP1 (0.41) | TDP1LMNA | |
| SCHEMBL19121759 | 0.77 | LMNA (0.32) | LMNA | |
| SCHEMBL20921769 | 0.77 | LMNA (0.32) | LMNA | |
| SCHEMBL20099378 | 0.76 | ADH1B (0.32) | TDP1 | |
| SCHEMBL12703373 | 0.75 | TDP1 (0.44) | TDP1LMNA | |
| SCHEMBL13995936 | 0.75 | TDP1 (0.44) | TDP1LMNA | |
| SCHEMBL13995874 | 0.75 | TDP1 (0.44) | TDP1LMNA | |
| SCHEMBL19969956 | 0.75 | SLC6A4 (0.33) | — | |
| SCHEMBL19986440 | 0.74 | TDP1 (0.50) | TDP1 | |
| SCHEMBL24288643 | 0.74 | TDP1 (0.37) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | TAKEDA CALIFORNIA, INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | HTR3A, HTR3B, HTR5A | TDP1 2555/4885LMNA 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.