Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017499 | 0.69 | TGM2 (0.49) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL7816692 | 0.67 | POLB (0.66) | TGM2POLBTDP1MEN1HTT | |
| SCHEMBL20057973 | 0.67 | MEN1 (0.50) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL25930070 | 0.66 | TGM2 (0.45) | TGM2POLBTDP1MAPTNPC1 | |
| SCHEMBL18599481 | 0.66 | HPGD (0.48) | POLBTDP1MEN1CYP1A2CYP3A4 | |
| SCHEMBL21160651 | 0.66 | HDAC3 (0.51) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL21416943 | 0.66 | ALDH1A1 (0.45) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL10057892 | 0.65 | TDP1 (0.60) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL23607581 | 0.65 | TDP1 (0.54) | TGM2POLBTDP1MEN1CYP1A2 | |
| SCHEMBL25769933 | 0.65 | TGM2 (0.47) | TGM2POLBTDP1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984534-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | Peking University (CN) | 2022-04-20 | — | — | EP | disclosed |