Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791511 | 0.81 | CYP3A4 (0.39) | LMNAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20931145 | 0.79 | KDM4E (0.36) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL22791569 | 0.79 | GAA (0.35) | LMNAMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL1015921 | 0.73 | RECQL (0.60) | STAT3LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL19827908 | 0.73 | IDO1 (0.40) | LMNAMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL24290481 | 0.72 | STAT3 (0.41) | STAT3LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL13535931 | 0.72 | MAPT (0.40) | STAT3LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL24289562 | 0.72 | STAT3 (0.41) | STAT3LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL21861846 | 0.72 | ALDH1A1 (0.43) | STAT3LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL31708248 | 0.72 | LMNA (0.49) | STAT3LMNAMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |