Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19132723 | 0.78 | OPRL1 (0.50) | OPRL1 | |
| SCHEMBL14662046 | 0.78 | HRH3 (0.36) | OPRL1 | |
| SCHEMBL574979 | 0.78 | — | — | |
| SCHEMBL12774192 | 0.76 | HRH3 (0.37) | OPRL1OPRM1 | |
| SCHEMBL19132728 | 0.75 | RORC (0.36) | OPRL1OPRM1 | |
| SCHEMBL4825714 | 0.74 | HTR6 (0.41) | OPRL1OPRM1 | |
| SCHEMBL736256 | 0.74 | SLC18A3 (0.42) | — | |
| SCHEMBL18202930 | 0.74 | HRH3 (0.33) | OPRL1OPRM1 | |
| SCHEMBL735809 | 0.74 | L3MBTL3 (0.38) | — | |
| SCHEMBL1394992 | 0.73 | L3MBTL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768948-B | Alternatively 4- formamido group-isoindoline ketone derivatives of property PARP-1 inhibitor | 内尔维阿诺医学科学有限公司 | 2018-11-27 | — | — | CN | disclosed |
| EP-2549874-A1 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS BETA-SECRETASE INHIBITORS | High Point Pharmaceuticals, LLC (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119465-A1 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS BETA-SECRETASE INHIBITORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-09-29 | — | — | WO | disclosed |