Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151163 | 0.86 | HPGD (0.54) | VNN1ATMRAB9AHPGDMEN1 | |
| SCHEMBL22151158 | 0.86 | VNN1 (0.53) | VNN1ATMRAB9AALDH1A1KMT2A | |
| SCHEMBL29606940 | 0.86 | VNN1 (0.53) | VNN1ATMRAB9AALDH1A1KMT2A | |
| SCHEMBL22151164 | 0.86 | HPGD (0.54) | VNN1ATMRAB9AHPGDMEN1 | |
| SCHEMBL29606733 | 0.86 | HPGD (0.54) | VNN1ATMRAB9AHPGDMEN1 | |
| SCHEMBL22151143 | 0.86 | VNN1 (0.53) | VNN1ATMRAB9AALDH1A1KMT2A | |
| SCHEMBL25761305 | 0.84 | GPR139 (0.49) | VNN1ATMRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29607531 | 0.83 | MEN1 (0.50) | VNN1ATMALDH1A1HPGDMEN1 | |
| SCHEMBL22151116 | 0.83 | MEN1 (0.50) | VNN1ATMALDH1A1HPGDMEN1 | |
| SCHEMBL22151113 | 0.83 | MEN1 (0.50) | VNN1ATMALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834391-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-12-05 | — | — | US | disclosed |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-05-25 | — | — | US | disclosed |
| US-11572336-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-02-07 | — | — | US | disclosed |
| US-20220073450-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572336-B2 | Pantothenamide analogues | NAMPT, VKORC1, NME4 | VNN1 5/4885ATM 4720/4885RAB9A 1274/4885 |
| US-20220073450-A1 | PANTOTHENAMIDE ANALOGUES | NAMPT, VKORC1, NME4 | VNN1 5/4885ATM 4720/4885RAB9A 1274/4885 |
| US-11834391-B2 | Pantothenamide analogues | NAMPT, VKORC1, NME4 | VNN1 5/4885ATM 4720/4885RAB9A 1274/4885 |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | NAMPT, VKORC1, NME4 | VNN1 5/4885ATM 4720/4885RAB9A 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.