Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151163 | 1.00 | HPGD (0.54) | HPGDATMNPC1LMNARAB9A | |
| SCHEMBL22151164 | 1.00 | HPGD (0.54) | HPGDATMNPC1LMNARAB9A | |
| SCHEMBL22151143 | 0.87 | VNN1 (0.53) | ATMNPC1LMNARAB9AGPR139 | |
| SCHEMBL29606940 | 0.87 | VNN1 (0.53) | ATMNPC1LMNARAB9AGPR139 | |
| SCHEMBL22151158 | 0.87 | VNN1 (0.53) | ATMNPC1LMNARAB9AGPR139 | |
| SCHEMBL24296115 | 0.86 | VNN1 (0.51) | HPGDATMNPC1RAB9AVNN1 | |
| SCHEMBL22151135 | 0.85 | VNN1 (0.43) | HPGDATMLMNAVNN1MEN1 | |
| SCHEMBL29606952 | 0.85 | VNN1 (0.43) | HPGDATMLMNAVNN1MEN1 | |
| SCHEMBL22151136 | 0.85 | VNN1 (0.43) | HPGDATMLMNAVNN1MEN1 | |
| SCHEMBL25761305 | 0.85 | GPR139 (0.49) | ATMNPC1LMNARAB9AGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834391-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-12-05 | — | — | US | disclosed |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-05-25 | — | — | US | disclosed |
| US-20220073450-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073450-A1 | PANTOTHENAMIDE ANALOGUES | NAMPT, VKORC1, NME4 | HPGD 80/4885ATM 4720/4885NPC1 281/4885 |
| US-11834391-B2 | Pantothenamide analogues | NAMPT, VKORC1, NME4 | HPGD 80/4885ATM 4720/4885NPC1 281/4885 |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | NAMPT, VKORC1, NME4 | HPGD 80/4885ATM 4720/4885NPC1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.