Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19457373 | 0.83 | HSD11B1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AMCOLN3 | |
| SCHEMBL22601463 | 0.80 | LMNA (0.56) | ALDH1A1USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21986228 | 0.75 | POLB (0.64) | ALDH1A1PKMUSP2SMN1; SMN2MEN1 | |
| SCHEMBL3466579 | 0.74 | UHRF1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHTTGAA | |
| SCHEMBL15010831 | 0.72 | ALDH1A1 (0.73) | ALDH1A1PKMUSP2MEN1KMT2A | |
| SCHEMBL12320892 | 0.72 | ALDH1A1 (0.69) | ALDH1A1PKMUSP2SMN1; SMN2MEN1 | |
| SCHEMBL13801171 | 0.72 | UHRF1 (0.48) | SMN1; SMN2 | |
| SCHEMBL12320941 | 0.71 | ALDH1A1 (0.67) | ALDH1A1USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27470371 | 0.71 | KDM4E (0.54) | ALDH1A1USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14317797 | 0.71 | CA1 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047288-A9 | METHODS OF TREATING CANCER | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) | 2022-03-31 | — | — | WO | disclosed |