Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839770 | 0.85 | SCD5 (0.47) | TACR1USP30SCD5GPR119 | |
| SCHEMBL30835857 | 0.82 | MAPT (0.43) | TACR1USP30MAPTSCD5GPR119 | |
| SCHEMBL20396116 | 0.80 | IDH1 (0.52) | TACR1USP30GPR119RORC | |
| SCHEMBL2424711 | 0.79 | YAP1 (0.46) | TACR1USP30SCD5GPR119 | |
| SCHEMBL20395989 | 0.77 | PDK2 (0.41) | TACR1MAPTGPR119RORC | |
| SCHEMBL20412572 | 0.76 | GRM5 (0.45) | SCD5GPR119POLB | |
| SCHEMBL19838850 | 0.75 | SCD5 (0.44) | USP30SCD5GPR119RORCHDAC1 | |
| SCHEMBL20396121 | 0.74 | PARP14 (0.45) | USP30SCD5GPR119HDAC1HDAC2 | |
| SCHEMBL13660794 | 0.74 | TACR1 (0.56) | TACR1 | |
| SCHEMBL13551815 | 0.74 | TACR1 (0.45) | TACR1USP30MAPTRXFP1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | FAAH, FAAH2, FFAR1 | TACR1 1103/4885USP30 1277/4885MAPT 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.