Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GAPDH | P04406 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517170 | 0.79 | RAB9A (0.78) | RAB9ANPC1MAOBALDH1A1KDM4E | |
| SCHEMBL927135 | 0.77 | RAB9A (0.54) | CHEK1KDRRAB9ANPC1MAOB | |
| SCHEMBL5076094 | 0.76 | KDR (1.00) | CHEK1KDRRAB9ANPC1ALDH1A1 | |
| SCHEMBL29370693 | 0.76 | KDR (1.00) | CHEK1KDRRAB9ANPC1ALDH1A1 | |
| SCHEMBL6254019 | 0.76 | RAB9A (0.58) | RAB9ANPC1MAOBALDH1A1KDM4E | |
| SCHEMBL28124981 | 0.76 | KDR (0.54) | CHEK1KDRRAB9ANPC1MAOB | |
| SCHEMBL6712737 | 0.76 | KDR (0.57) | CHEK1KDRRAB9ANPC1ALDH1A1 | |
| SCHEMBL4583148 | 0.75 | RAB9A (1.00) | KDRRAB9ANPC1MAOBALDH1A1 | |
| SCHEMBL5051826 | 0.73 | KDR (0.68) | CHEK1KDRRAB9ANPC1ALDH1A1 | |
| SCHEMBL177366 | 0.73 | RAB9A (1.00) | RAB9ANPC1MAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364318-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | Bio-Rad Laboratories, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010065514-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5501980-A | Benzazolylcoumarin-based ion indicators | MOLECULAR PROBES, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5501980-A | Benzazolylcoumarin-based ion indicators | MOLECULAR PROBES, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5459276-A | Chelate compounds for fluorescence | MOLECULAR PROBES, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| US-5459276-A | Chelate compounds for fluorescence | MOLECULAR PROBES, INC. (US) | 1995-10-17 | — | — | US | disclosed |