Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531027 | 0.81 | CA9 (0.64) | CA9SMN1; SMN2L3MBTL1MAPTCYP2C9 | |
| SCHEMBL27032736 | 0.78 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL4947232 | 0.77 | MAOB (0.61) | CA9SMN1; SMN2L3MBTL1MAPTCYP2C9 | |
| SCHEMBL3307110 | 0.76 | MAPT (0.56) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL23640344 | 0.76 | MAPK14 (0.50) | SMN1; SMN2L3MBTL1MAPTTDP1PPIA | |
| SCHEMBL27656755 | 0.75 | KDM4E (0.46) | SMN1; SMN2L3MBTL1MAPTTDP1LTA4H | |
| SCHEMBL4691988 | 0.75 | LTA4H (0.55) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL29836285 | 0.75 | LTA4H (0.55) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL2799479 | 0.74 | LTA4H (0.58) | SMN1; SMN2L3MBTL1MAPTTDP1PPIA | |
| SCHEMBL27592091 | 0.74 | LMNA (0.46) | MAPTLTA4HMAPK14MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119376-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119376-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | CRBN, CSNK2A1, CSNK2A2 | CA9 3412/4885SMN1; SMN2 2099/4885L3MBTL1 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.