Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147524 | 0.83 | MAPT (0.65) | MAPTSMN1; SMN2L3MBTL1TDP1CYP2C9 | |
| SCHEMBL18428699 | 0.83 | MAPT (0.65) | MAPTSMN1; SMN2L3MBTL1TDP1CYP2C9 | |
| SCHEMBL16407670 | 0.79 | PSMD14 (0.53) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL28594857 | 0.78 | LIPE (0.55) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL10333926 | 0.78 | KDM4E (0.57) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL24303045 | 0.76 | CA9 (0.52) | MAPTSMN1; SMN2L3MBTL1TDP1CYP2C9 | |
| SCHEMBL3976299 | 0.76 | KDM4E (0.63) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL29862716 | 0.76 | SLC40A1 (0.50) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL13625118 | 0.76 | SLC40A1 (0.50) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E | |
| SCHEMBL6600225 | 0.76 | LTA4H (0.58) | MAPTSMN1; SMN2L3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132179-B1 | PROCESS FOR PREPARING ISOMERS OF CARMOTEROL | CIPLA LTD (IN) | 2012-08-08 | — | — | EP | disclosed |
| US-8236959-B2 | Process for preparing isomers of carmoterol | CIPLA LIMITED (IN) | 2012-08-07 | — | — | US | disclosed |
| US-8236959-B2 | Process for preparing isomers of carmoterol | CIPLA LIMITED (IN) | 2012-08-07 | — | — | US | disclosed |
| US-8236959-B2 | Process for preparing isomers of carmoterol | CIPLA LIMITED (IN) | 2012-08-07 | — | — | US | disclosed |
| US-20100113790-A1 | Process for Preparing Isomers of Carmoterol | CIPLA LIMITED (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113790-A1 | Process for Preparing Isomers of Carmoterol | CIPLA LIMITED (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113790-A1 | Process for Preparing Isomers of Carmoterol | CIPLA LIMITED (IN) | 2010-05-06 | — | — | US | disclosed |
| EP-2132179-A1 | PROCESS FOR PREPARING ISOMERS OF CARMOTEROL | Cipla Limited (IN) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008104781-A1 | PROCESS FOR PREPARING ISOMERS OF CARMOTEROL | CIPLA LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008104781-A1 | PROCESS FOR PREPARING ISOMERS OF CARMOTEROL | CIPLA LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |
| US-RE33024-E | Bronchodilating 8-hydroxy-5-(1R)-1-hydroxy-2-(N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino)ethyl) carbostyril and intermediates thereof | TANABE SEIYAKU CO. LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0147719-B1 | NOVEL CARBOSTYRIL DERIVATIVE AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4579854-A | ADRENERGIC STIMULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
| EP-0147719-A2 | Novel carbostyril derivative and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113790-A1 | Process for Preparing Isomers of Carmoterol | NR1H2, NR1H3, ADRB1 | MAPT 4670/4885SMN1; SMN2 3364/4885L3MBTL1 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.