SCHEMBL2430387

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7261286	0.89	ALDH1A1 (0.56)	ALDH1A1KDM4EHPGDPLK4AURKA
	SCHEMBL7260711	0.83	KDM4E (0.62)	ALDH1A1KDM4EHPGDDYRK1ATNKS
	SCHEMBL2432181	0.81	HPGD (0.43)	ALDH1A1KDM4EHPGDPLK4AURKA
	SCHEMBL7261295	0.76	CDK4 (0.60)	ALDH1A1KDM4EHPGDPLK4AURKA
	SCHEMBL2438245	0.76	MEN1 (0.39)	ALDH1A1PLK4AURKANUAK1CDK4
	SCHEMBL2429171	0.75	MEN1 (0.39)	ALDH1A1PLK4AURKANUAK1CDK4
	SCHEMBL2430131	0.74	ALDH1A1 (0.40)	ALDH1A1KDM4EHPGDPLK4AURKA
	SCHEMBL28860747	0.71	PARP1 (0.66)	ALDH1A1KDM4EHPGDPLK4AURKA
	SCHEMBL7256679	0.70	PLK4 (0.47)	ALDH1A1KDM4EPLK4AURKANUAK1
	SCHEMBL2430302	0.70	ALDH1A1 (0.46)	ALDH1A1KDM4EDYRK1ACYP1A2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.