SCHEMBL2438245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2429171	0.99	MEN1 (0.39)	MEN1KMT2AALDH1A1CDK4CCND1
	SCHEMBL2430131	0.93	ALDH1A1 (0.40)	MEN1KMT2AALDH1A1CDK4CCND1
	SCHEMBL2430461	0.86	KDM4E (0.39)	MEN1KMT2AALDH1A1PPARATSHR
	SCHEMBL2429246	0.85	TSHR (0.38)	MEN1KMT2AALDH1A1LMNAMAPT
	SCHEMBL2432181	0.81	HPGD (0.43)	ALDH1A1CDK4CCND1MAPTPLK4
	SCHEMBL7261286	0.81	ALDH1A1 (0.56)	MEN1KMT2AALDH1A1CDK4CCND1
	SCHEMBL2430387	0.76	ALDH1A1 (0.47)	MEN1KMT2AALDH1A1CDK4CCND1
	SCHEMBL7261295	0.73	CDK4 (0.60)	MEN1KMT2AALDH1A1CDK4CCND1
	SCHEMBL2429922	0.73	DCTPP1 (0.37)	MEN1KMT2AALDH1A1MAPTMTNR1A
	SCHEMBL2434644	0.72	HRH3 (0.39)	MEN1KMT2AALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.