SCHEMBL24304376

SCHEMBL24304376

CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC[C@@H]1CC[C@](C)(c2ccc3c(N)ncnn23)O1)OCc1ccc(OC)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TBXAS1 P24557 2/20 0.34
▸ LPAR1 Q92633 2/20 0.31
▸ LPAR3 Q9UBY5 2/20 0.31
▸ P2RY10 O00398 1/20 0.30
▸ AKT1 P31749 2/20 0.30
▸ PLCG2 P16885 1/20 0.30
▸ PIK3R1 P27986 1/20 0.30
▸ AKT2 P31751 1/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ AKT3 Q9Y243 1/20 0.30
▸ GAB1 Q13480 1/20 0.30
▸ FGFR1 P11362 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24305343 0.93 LPAR1 (0.31) LPAR1LPAR3FGFR1PLA2G2C
SCHEMBL24304696 0.93 TLR2 (0.32) LPAR1LPAR3P2RY10FGFR1PLA2G2C
SCHEMBL24305037 0.92 SLC6A5 (0.30) LPAR1LPAR3
SCHEMBL24305108 0.90 — —
SCHEMBL25972298 0.90 TBXAS1 (0.33) TBXAS1CYP3A4CYP2D6
SCHEMBL24305346 0.90 S1PR1 (0.31) —
SCHEMBL24304666 0.88 PLA2G10 (0.32) —
SCHEMBL24304912 0.87 TBXAS1 (0.34) TBXAS1AKT1PLCG2PIK3R1AKT2
SCHEMBL25969532 0.87 TBXAS1 (0.34) TBXAS1AKT1PLCG2PIK3R1AKT2
SCHEMBL24304638 0.86 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TBXAS1 255/4885LPAR1 87/4885LPAR3 108/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TBXAS1 255/4885LPAR1 87/4885LPAR3 108/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 TBXAS1 255/4885LPAR1 87/4885LPAR3 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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