Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 4/20 | 0.31 |
| ▸ | AKT2 | P31751 | 3/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.31 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304912 | 1.00 | TBXAS1 (0.34) | TBXAS1AKT1AKT2AKT3PIK3R1 | |
| SCHEMBL27458088 | 0.94 | POLRMT (0.32) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL25973647 | 0.94 | POLRMT (0.32) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL25970130 | 0.94 | POLRMT (0.32) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL25973662 | 0.94 | POLRMT (0.32) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL25971253 | 0.93 | POLRMT (0.32) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL25969778 | 0.93 | ADK (0.36) | POLRMTADK | |
| SCHEMBL25969236 | 0.93 | ADK (0.36) | POLRMTADK | |
| SCHEMBL24407333 | 0.93 | ADK (0.36) | POLRMTADK | |
| SCHEMBL24304772 | 0.93 | PLA2G2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030904-B2 | Phospholipid compounds and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240025932-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| US-11773122-B2 | Phospholipid compounds and uses thereof | GILEAD SCIENCES. INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230250117-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030904-B2 | Phospholipid compounds and uses thereof | PHOSPHO1, SGMS2, SGMS1 | TBXAS1 255/4885AKT1 1942/4885AKT2 1473/4885 |
| US-20230250117-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | PHOSPHO1, SGMS2, SGMS1 | TBXAS1 255/4885AKT1 1942/4885AKT2 1473/4885 |
| US-20240025932-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | PHOSPHO1, SGMS2, SGMS1 | TBXAS1 255/4885AKT1 1942/4885AKT2 1473/4885 |
| US-11773122-B2 | Phospholipid compounds and uses thereof | PHOSPHO1, SGMS2, SGMS1 | TBXAS1 255/4885AKT1 1942/4885AKT2 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.