Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 3/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944734 | 0.80 | ALB (0.38) | ALBSIRT5SIRT6SIRT1KMT2A | |
| SCHEMBL23772124 | 0.80 | ALB (0.41) | ALBSIRT5ALDH1A1TLR2 | |
| SCHEMBL26379449 | 0.79 | SIRT6 (0.40) | ALBSIRT5SIRT6SIRT1KMT2A | |
| SCHEMBL21389124 | 0.78 | CASP2 (0.51) | ALBSIRT6SIRT1KMT2AMEN1 | |
| SCHEMBL27342049 | 0.78 | EPHX2 (0.47) | ALBSIRT5FOLH1TLR2KDM4E | |
| SCHEMBL27342047 | 0.78 | EPHX2 (0.47) | ALBSIRT5FOLH1TLR2KDM4E | |
| SCHEMBL23330799 | 0.77 | ALB (0.41) | ALBSIRT5KMT2AMEN1FOLH1 | |
| SCHEMBL24958429 | 0.77 | KDM4E (0.35) | ALBSIRT5SIRT6SIRT1ALDH1A1 | |
| SCHEMBL27309897 | 0.77 | KISS1R (0.39) | ALBSIRT5SIRT6SIRT1EPHX1 | |
| SCHEMBL13402566 | 0.74 | NPY4R (0.42) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | JEFFREY W. AND CHRISTINA R. BIRD TRUST U/A/D | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | IL2RA, IL2, IL15RA | ALB 1468/4885SIRT5 3098/4885SIRT6 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.