Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330506 | 0.86 | PGR (0.42) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL29566821 | 0.86 | PGR (0.42) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL24330507 | 0.74 | FFAR1 (0.33) | FFAR1F10MAPTCYP2C19ALDH1A1 | |
| SCHEMBL24310597 | 0.74 | TDP1 (0.44) | KMT2AMAPTALDH1A1 | |
| SCHEMBL29566742 | 0.73 | LMNA (0.43) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL24330505 | 0.73 | LMNA (0.43) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL24330653 | 0.73 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL24310009 | 0.72 | GPR39 (0.45) | MEN1KMT2AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL24298101 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2AMAPTCYP3A4ALDH1A1 | |
| SCHEMBL24298137 | 0.71 | GPR39 (0.35) | F10MEN1KMT2AMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |