Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | YES1 | P07947 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310515 | 0.84 | — | — | |
| SCHEMBL24309949 | 0.83 | MAP4K1 (0.31) | — | |
| SCHEMBL24310507 | 0.77 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL24310009 | 0.77 | GPR39 (0.45) | — | |
| SCHEMBL24310499 | 0.72 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL24299252 | 0.69 | CYP1A2 (0.40) | SRC | |
| SCHEMBL22509298 | 0.68 | CYP1A2 (0.40) | SRC | |
| SCHEMBL24329987 | 0.68 | PLK1 (0.35) | — | |
| SCHEMBL11291403 | 0.68 | TSHR (0.46) | — | |
| SCHEMBL11289134 | 0.67 | AGTR1 (0.56) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |