Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310807 | 0.93 | PTGS2 (0.30) | — | |
| SCHEMBL24310360 | 0.91 | KDM4E (0.33) | KDM5AKDM4E | |
| SCHEMBL24309830 | 0.88 | IGF1R (0.32) | IGF1R | |
| SCHEMBL24309901 | 0.87 | IGF1R (0.33) | IGF1R | |
| SCHEMBL24310179 | 0.87 | IGF1R (0.31) | IGF1R | |
| SCHEMBL24309917 | 0.87 | MAPK14 (0.33) | IGF1R | |
| SCHEMBL24310590 | 0.86 | IGF1R (0.31) | IGF1R | |
| SCHEMBL24309378 | 0.85 | IGF1R (0.30) | IGF1R | |
| SCHEMBL24309438 | 0.84 | GABRG2 (0.30) | IGF1R | |
| SCHEMBL24310417 | 0.84 | LMNA (0.33) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |