SCHEMBL24311024

SCHEMBL24311024

Brc1ccc(-n2c3ccccc3c3ccccc32)c2nc(-c3ccccc3)c(-c3ccccc3)nc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
ATM Q13315 1/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 4/20 0.36
POLB P06746 2/20 0.34
DHODH Q02127 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HPGD P15428 3/20 0.33
HSD17B10 Q99714 2/20 0.33
PTGER1 P34995 1/20 0.33
LMNA P02545 1/20 0.33
DHFR P00374 1/20 0.33
PIK3CG P48736 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20230536 0.91 KDM4E (0.44) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL24310920 0.82 ALDH1A1 (0.40) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL21778283 0.80 KDM4E (0.48) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL21778276 0.80 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL29423330 0.79 DHFR (0.46) KDM4EL3MBTL1KMT2AMAPTMAPK1
SCHEMBL1322385 0.79 DHFR (0.46) KDM4EL3MBTL1KMT2AMAPTMAPK1
SCHEMBL20230486 0.78 KDM4E (0.38) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL21778275 0.76 NPY5R (0.37) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL20230487 0.75 KDM4E (0.36) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL17739645 0.75 HTT (0.42) KDM4EL3MBTL1ATMKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022062597-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND USE THEREOF 浙江百可半导体材料有限公司 2022-03-31 WO disclosed