Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230536 | 0.88 | KDM4E (0.44) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL21778276 | 0.87 | KDM4E (0.42) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL11947031 | 0.87 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL12268646 | 0.84 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL21778201 | 0.83 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL24310920 | 0.83 | ALDH1A1 (0.40) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL17879118 | 0.83 | L3MBTL1 (0.55) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL1303909 | 0.81 | KDM4E (0.53) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL21778197 | 0.81 | L3MBTL1 (0.48) | KDM4EL3MBTL1ATMHDAC4ALDH1A1 | |
| SCHEMBL24311024 | 0.80 | KDM4E (0.37) | KDM4EL3MBTL1ATMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577325-B2 | Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577325-B2 | Method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes | CYBA, PPOX, IK | KDM4E 2154/4885L3MBTL1 431/4885ATM 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.