Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10125720 | 0.91 | CTSD (0.65) | CTSDCNR1FAAHCASP2DNM1 | |
| SCHEMBL9104575 | 0.87 | CNR1 (0.51) | CTSDCNR1FAAHCASP2TSHR | |
| SCHEMBL16302656 | 0.86 | FAAH (0.63) | CNR1FAAHCASP2TSHRDNM1 | |
| SCHEMBL9823629 | 0.85 | CASP2 (0.59) | CTSDCNR1FAAHCASP2DNM1 | |
| SCHEMBL19703760 | 0.84 | FAAH (0.65) | CNR1FAAHCASP2TSHRDNM1 | |
| SCHEMBL22992630 | 0.84 | CASP2 (0.63) | CNR1FAAHCASP2TSHRDNM1 | |
| SCHEMBL700736 | 0.84 | CASP2 (0.61) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL13492301 | 0.84 | CTSD (0.47) | CTSDCNR1FAAHCASP2TSHR | |
| SCHEMBL8816533 | 0.83 | EPHX2 (0.57) | CNR1FAAHCASP2TSHRSLC6A5 | |
| SCHEMBL2607955 | 0.83 | CNR1 (0.51) | CNR1FAAHCASP2TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076905-A1 | ALK5 INHIBITORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |