SCHEMBL9104575

SCHEMBL9104575

CCCNC(=O)CCCC(N)=O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.51
FAAH O00519 4/20 0.50
CASP2 P42575 1/20 0.50
TSHR P16473 1/20 0.48
DNM1 Q05193 2/20 0.47
NAAA Q02083 1/20 0.47
MCL1 Q07820 1/20 0.45
SLC6A5 Q9Y345 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CTSD P07339 1/20 0.43
ALDH1A1 P00352 1/20 0.42
EPHX1 P07099 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25825165 0.96 FAAH (0.55) CNR1FAAHCASP2TSHRDNM1
SCHEMBL29637706 0.94 FAAH (0.58) CNR1FAAHCASP2DNM1NAAA
SCHEMBL29637697 0.94 FAAH (0.58) CNR1FAAHCASP2DNM1NAAA
SCHEMBL29637720 0.94 FAAH (0.58) CNR1FAAHCASP2DNM1NAAA
SCHEMBL16924465 0.94 FAAH (0.58) CNR1FAAHCASP2DNM1NAAA
SCHEMBL29637705 0.94 FAAH (0.58) CNR1FAAHCASP2DNM1NAAA
Hexadecanoic Acid Propylamide SCHEMBL16398673 0.90 FAAH (0.65) CNR1FAAHCASP2DNM1NAAA
SCHEMBL6686395 0.89 CASP2 (0.59) CNR1FAAHCASP2TSHRDNM1
SCHEMBL1298444 0.89 CASP2 (0.47) CNR1FAAHCASP2DNM1NAAA
SCHEMBL24312136 0.87 CTSD (0.60) CNR1FAAHCASP2TSHRDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022038417-A2 MODIFIED IL-18 POLYPEPTIDES AND USES THEREOF BRIGHT PEAK THERAPEUTICS AG (CH) 2022-02-24 WO disclosed
EP-3733683-A1 NUCLEOSIDE ANALOGUE, PREPARATION METHOD AND APPLICATION GeneMind Biosciences Company Limited (CN) 2020-11-04 EP disclosed
EP-2460885-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED GLUTARIC ACID MONOAMIDE Kaneka Corporation (JP) 2012-06-06 EP disclosed