Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314320 | 0.87 | SCN9A (0.38) | BCAT1PTGER4 | |
| SCHEMBL29587417 | 0.87 | SCN9A (0.38) | BCAT1PTGER4 | |
| SCHEMBL24313633 | 0.86 | HPGD (0.44) | BCAT1PTGER4HPGDKDM4EMEN1 | |
| SCHEMBL29588075 | 0.82 | HIF1A (0.37) | BCAT1PTGER4MEN1KMT2A | |
| SCHEMBL24313751 | 0.82 | PTGER4 (0.40) | BCAT1PTGER4HPGDKDM4EMEN1 | |
| SCHEMBL24313906 | 0.81 | PTGER4 (0.45) | BCAT1PTGER4HPGDF11PTGS1 | |
| SCHEMBL22587694 | 0.80 | PTGER4 (0.40) | BCAT1PTPN1PTGER4HPGDKDM4E | |
| SCHEMBL24313801 | 0.79 | RAB9A (0.36) | HPGDKDM4EMEN1KMT2ALMNA | |
| SCHEMBL29588270 | 0.79 | HSD17B10 (0.39) | BCAT1ALDH1A1NPC1RAB9APPARG | |
| SCHEMBL24313926 | 0.79 | MCL1 (0.42) | HPGDKDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |