Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314242 | 0.87 | PTGER4 (0.37) | PTGER4ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL29587615 | 0.87 | PTGER4 (0.37) | PTGER4ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL24313633 | 0.84 | HPGD (0.44) | PTGER4BCAT1CA12CA9PTGS1 | |
| SCHEMBL29588267 | 0.82 | GAA (0.35) | PTGER4ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL24313796 | 0.82 | RBP4 (0.42) | PTGER4BCAT1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL29587778 | 0.79 | HSD17B10 (0.39) | ALDH1A1HTTSMN1; SMN2NPSR1RAB9A | |
| SCHEMBL24314312 | 0.79 | HSD17B10 (0.39) | ALDH1A1HTTSMN1; SMN2NPSR1RAB9A | |
| SCHEMBL24313906 | 0.79 | PTGER4 (0.45) | PTGER4BCAT1PTGS1PTGS2HPGD | |
| SCHEMBL24313756 | 0.79 | LMNA (0.33) | ALDH1A1GAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL24313929 | 0.79 | MCL1 (0.38) | PTGS1ALDH1A1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |