Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.39 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099803 | 0.93 | SYK (0.41) | KDM4EALDH1A1L3MBTL1CSF1RMEN1 | |
| SCHEMBL19066170 | 0.75 | MEN1 (0.51) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL24506589 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL24506584 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL18334824 | 0.74 | GRM5 (0.34) | KDM4EMEN1KMT2ANOS3NOS1 | |
| SCHEMBL23304425 | 0.73 | HCAR3 (0.48) | KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL30290183 | 0.73 | HCAR3 (0.48) | KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL17054985 | 0.73 | KIT (0.41) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11169098 | 0.72 | EPHX1 (0.49) | KDM4EALDH1A1CSF1RGAAMEN1 | |
| SCHEMBL31633780 | 0.72 | S1PR1 (0.45) | KDM4EALDH1A1L3MBTL1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS INC (US) | 2024-02-15 | — | — | US | disclosed |
| CN-117098767-A | METTL3 modulators | 埃克森特治疗公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4229067-A1 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051985-A1 | METTL3 MODULATORS | METTL3, METTL16, METTL14 | KDM4E 692/4885ALDH1A1 829/4885L3MBTL1 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.