Sugi Predict

Sugi Predict / Compounds / SCHEMBL2431486

SCHEMBL2431486

SCHEMBL2431486

CCOC(=O)C1CC=C(C)CC1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.51
▸ TSHR P16473 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ PDK1 Q15118 1/20 0.42
▸ MAPT P10636 2/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31601392 1.00 LMNA (0.51) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL29777417 0.91 TSHR (0.46) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL23091554 0.91 TSHR (0.46) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL10939987 0.90 ALOX15 (0.45) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL4324700 0.90 LMNA (0.51) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL17616822 0.90 LMNA (0.51) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL4322994 0.87 LMNA (0.46) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL15481289 0.86 LMNA (0.45) LMNATSHRALOX15MAPK1ALDH1A1
SCHEMBL10940431 0.85 ALOX15 (0.46) TSHRALOX15MAPK1ALDH1A1NPC1
SCHEMBL12519547 0.85 ALOX15 (0.49) TSHRALOX15MAPK1ALDH1A1PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600707-B2 Cannabinoid derivatives, precursors and uses KARE CHEMICAL TECHNOLOGIES INC. (CA) 2026-04-14 — — US disclosed
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-07-13 — — US disclosed
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE THERAVANCE BIOPHARMA R&D IP LLC (US) 2023-07-13 — — US disclosed
US-20230192709-A1 FGFR INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS, INC. 2023-06-22 — — US disclosed
US-20230104574-A1 FGFR INHIBITORS AND METHODS OF USE THEREOF D.E. SHAW RESEARCH, LLC 2023-04-06 — — US disclosed
US-11590116-B2 Substituted pyridines and methods of use THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-02-28 — — US disclosed
US-20220380333-A1 CANNABINOID DERIVATIVES, PRECURSORS AND USES KARE CHEMICAL TECHNOLOGIES INC. (CA) 2022-12-01 — — US disclosed
CN-114981235-A Cannabinoid derivatives, precursors and uses 卡瑞化学技术公司 2022-08-30 — — CN disclosed
EP-4028381-A1 CANNABINOID DERIVATIVES, PRECURSORS AND USES Kare Chemical Technologies Inc. (CA) 2022-07-20 — — EP disclosed
WO-2021102468-A1 SUBSTITUTED 1,5-NAPHTHYRIDINES OR QUINOLINES AS ALK5 INHIBITORS THERAVANCE BIOPHARMA R&D IP, LLC (US) 2021-05-27 — — WO disclosed
US-20140200215-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. 2014-07-17 — — US disclosed
EP-2086966-B1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2011-09-14 — — EP disclosed
EP-2086966-B1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2011-09-14 — — EP disclosed
US-20090274655-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION 2009-11-05 — — US disclosed
US-20090274655-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION 2009-11-05 — — US disclosed
US-20090274655-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION 2009-11-05 — — US disclosed
CN-100439321-C Terpinene-4-ol derivative and its use HARMLESS PESTICIDE RES AND SER (CN) 2008-12-03 — — CN disclosed
WO-2008059042-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2008-05-22 — — WO disclosed
US-7195719-B1 High polarization ferroelectric liquid crystal compositions DISPLAYTECH, INC. (US) 2007-03-27 — — US disclosed
CN-1676511-A Terpinene-4-ol derivative and its use HARMLESS PESTICIDE RES AND SER (CN) 2005-10-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192709-A1 FGFR INHIBITORS AND METHODS OF USE THEREOF FGFR3, FGFR2, FGFR1 LMNA 4182/4885TSHR 3338/4885ALOX15 2774/4885
US-20230104574-A1 FGFR INHIBITORS AND METHODS OF USE THEREOF FGFR3, FGFR2, FGFR1 LMNA 4182/4885TSHR 3338/4885ALOX15 2774/4885
US-12600707-B2 Cannabinoid derivatives, precursors and uses CNR1, CNR2, GPR18 LMNA 4105/4885TSHR 697/4885ALOX15 1611/4885
US-20090274655-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS EIF2AK2, HAVCR2, GTF3C2 LMNA 4420/4885TSHR 1343/4885ALOX15 4295/4885
US-20220380333-A1 CANNABINOID DERIVATIVES, PRECURSORS AND USES CNR2, CNR1, FAAH LMNA 3130/4885TSHR 3533/4885ALOX15 1229/4885
US-20140200215-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS LPAR1, LPAR2, LPAR5 LMNA 701/4885TSHR 449/4885ALOX15 183/4885
US-20230218597-A1 SUBSTITUTED PYRIDINES AND METHODS OF USE ALK, ACVR1, ACVR2A LMNA 2060/4885TSHR 659/4885ALOX15 3795/4885
US-11590116-B2 Substituted pyridines and methods of use ALK, ACVR1, ACVR2A LMNA 2060/4885TSHR 659/4885ALOX15 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.