SCHEMBL2431593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2434988	0.88	MAOB (0.42)	HRH3DYRK1AMGAMGAASI
	SCHEMBL2432181	0.84	HPGD (0.43)	HRH3CYP1A2DYRK1AIDO1KDM4E
	SCHEMBL2432694	0.80	CYP19A1 (0.40)	HRH3CYP1A2CYP3A4CYP2C19MAOB
	SCHEMBL2461065	0.80	KDM4E (0.40)	HRH3DYRK1AGAAKDM4EALDH1A1
	SCHEMBL2432282	0.79	NPC1 (0.37)	CYP3A4DYRK1AMGAMGAASI
	SCHEMBL2432159	0.79	NPC1 (0.37)	HRH3CYP3A4DYRK1AMGAMGAA
	SCHEMBL1135960	0.78	MAOB (0.41)	HRH3CYP3A4DYRK1AMGAMGAA
	SCHEMBL2433158	0.78	ALDH1A1 (0.39)	HRH3CYP3A4DYRK1AMGAMGAA
	SCHEMBL2432114	0.76	NPC1 (0.37)	HRH3CYP3A4DYRK1AMGAMGAA
	SCHEMBL2435017	0.76	MGAM (0.42)	CYP3A4DYRK1AMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.