SCHEMBL2432694

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2431593	0.80	HRH3 (0.39)	CYP1A2CYP3A4CYP2C19MAOBHRH3
	SCHEMBL2434988	0.79	MAOB (0.42)	MAOAMAOBKMT2AKDRHRH3
	SCHEMBL2432181	0.75	HPGD (0.43)	CYP1A2KDRHRH3ATM
	SCHEMBL2462928	0.73	PDE5A (0.41)	HRH3GSK3B
	SCHEMBL2461065	0.71	KDM4E (0.40)	KDRHRH3
	SCHEMBL1135960	0.70	MAOB (0.41)	CYP3A4MAOAMAOBKMT2AKDR
	SCHEMBL2433158	0.70	ALDH1A1 (0.39)	CYP3A4MAOAMAOBKMT2AHRH3
	SCHEMBL2435481	0.69	CYP19A1 (0.41)	CYP19A1MAOAMAOBCYP11B1CYP11B2
	SCHEMBL2432282	0.69	NPC1 (0.37)	CYP3A4MAOAMAOBKMT2AMEN1
	SCHEMBL2432159	0.69	NPC1 (0.37)	CYP3A4KMT2AKDRHRH3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.