Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316412 | 0.84 | CYP11B1 (0.48) | ALOX5SIGMAR1 | |
| SCHEMBL24316419 | 0.80 | PDGFRB (0.49) | — | |
| SCHEMBL24316421 | 0.78 | CALM1 (0.47) | TAAR1MEN1KMT2A | |
| SCHEMBL24316416 | 0.77 | TAAR1 (0.49) | TAAR1ABCB1ALOX5 | |
| SCHEMBL324131 | 0.73 | CYP3A4 (0.46) | ALOX5 | |
| SCHEMBL21327653 | 0.72 | CSF1R (0.54) | — | |
| SCHEMBL24316420 | 0.72 | MAOB (0.45) | — | |
| SCHEMBL24316985 | 0.71 | MRGPRX4 (0.49) | MEN1KMT2A | |
| SCHEMBL30682056 | 0.71 | CSF1R (0.42) | TAAR1IDO1 | |
| SCHEMBL24316986 | 0.71 | KDM4E (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |