Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316421 | 0.87 | CALM1 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL24316419 | 0.87 | PDGFRB (0.49) | — | |
| SCHEMBL24316416 | 0.87 | TAAR1 (0.49) | CYP11B1CYP11B2ALOX5DRD2 | |
| SCHEMBL24316417 | 0.84 | TAAR1 (0.47) | ALOX5SIGMAR1 | |
| SCHEMBL24316986 | 0.75 | KDM4E (0.50) | — | |
| SCHEMBL14485783 | 0.74 | ABCB1 (0.48) | ALOX5 | |
| SCHEMBL324131 | 0.74 | CYP3A4 (0.46) | ALOX5 | |
| SCHEMBL24316420 | 0.74 | MAOB (0.45) | SCN9A | |
| SCHEMBL21327653 | 0.74 | CSF1R (0.54) | — | |
| SCHEMBL29256760 | 0.74 | TUBB4A (0.56) | ALOX5ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |